Terminal 2q Deletion and Distal 15q Duplication: Prenatal Diagnosis by Array Comparative Genomic Hybridization Using Uncultured Amniocytes
نویسندگان
چکیده
منابع مشابه
Terminal 2q deletion and distal 15q duplication: prenatal diagnosis by array comparative genomic hybridization using uncultured amniocytes.
A 35-year-old, gravida 3, para 2, woman was referred to the hospital at 18 weeks of gestation for amniocentesis because of advanced maternal age and relatives with balanced and unbalanced chromosomal translocations. Her husband and her elder daughter had a balanced translocation of t(2;15)(q37.3;q24.3). Her younger daughter suffered from mental retardation and had an unbalanced translocation of...
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Cytogenetic analysis is a crucial tool of prenatal diagnosis. The ability to rapidly detect aneuploidy and identify small structural abnormalities of foetal chromosomes has been greatly improved by the use of molecular cytogenetic technologies. Microarray-based Comparative Genomic Hybridization (aCGH) has been recently employed in postnatal diagnosis of cryptic chromosomal aberrations, but use ...
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Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan Department of Medical Research, Mackay Memorial Hospital, Taipei, Taiwan Department of Biotechnology, Asia University, Taichung, Taiwan d School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan e Institute of Clinical and Community Health Nursing, National Yang-Ming Univ...
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ژورنال
عنوان ژورنال: Taiwanese Journal of Obstetrics and Gynecology
سال: 2009
ISSN: 1028-4559
DOI: 10.1016/s1028-4559(09)60343-0